Uterine papillary serous carcinoma(UPSC) is a rare and highly malignant from of adenocarcinoma of the endometrium. Recently, a highly malignant variant of endometrial carcinoma, called uterine papillary serous carcinoma, has been described by
Hendrickson et al. It is similar both cytologically and histologically to ovarian epithelial neoplasms and has a poor prognosis even in early stage disease. Deep myometrial invasion nadvascular and lymphatic space involvement are frequently
identified
in hysterectomy specimens. In view of the poor prognosis of this disease entity, a means of estimating the likelihood for extrauterine metastases preoperatively and of monitoring the disease status of patients during and after therapy would be
advantageous.
Newer approaches will be needed to treat this biologically aggressive uterine cancer, which has usually spreaded beyond the uterine papillary serous carcinoma associated with metastasis to both ovaries, and salpinges, is given and the literatures
were
reviewed briefly.
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